SYnAbs' custom monoclonal antibody generation service is a one-stop shop solution allowing the generation of high quality specific antibodies for in-vitro diagnostic, R&D and therapeutic purposes. We run dozens of projects per year with high success rate for the raising of anti-drug antibodies, surrogates antibodies, or therapeutics mAbs from antigen design to gram manufacturing.
Stop wasting time & money !
Maximizing the success rate and the quality of your generated monoclonal antibodies in mice, alpagas, and SYnabs proprietary rats-LOU with parallel multi-species approach. Rat-LOU is known to be a particularly good responder to small molecules.
The diversity of the natural in-vivo immune repertoire is the key to the generation of higher affinity unprecedented monoclonal antibodies.
In need of a humanized mouse model? SYnAbs can work with you to access the complete functional human antibody repertoire through Alloy Therapeutics' ATX-Gx platform.
SYnabs has developed a variety of immunization types including chemical, peptide, proprietary SYnDNA immunization, SYnCell immunization, also with our in-house special adjuvant to boost the immune response.
SYnAbs offers variable immunization schedules and injection routes to benefit from natural antibody maturity, while breaking immune tolerance for small molecules, peptides and low-immunogenic compounds.
Thanks to smart antigen design strategies, SYnabs direct the immune response towards the most appropriate epitope. As a complete service, SYnAbs is able to design, synthesize and conjugate antigens for use as immunogen for your monoclonal antibody development program.
SYnabs has developed unique capabilities to isolate rare B populations from both primary and secondary lymphoid organs of the immune system.
Applying screening to hundreds of millions of enriched antibody-secreting plasmocytes cells, SYnAbs selects the rare antibodies with the desired unique effector properties you are looking for.
Neutralizing? inhibitor? agonist? antagonist? Make your choice.
SYnAbs cell culture services offer animal-free tissue culture based protocols in shake-flasks, spinners, CELLines, and FiberCell and provide scale-up activities for manufacturing up to several grams. We also perform monoclonal antibodies purification and cell storage banking services.
A large panel of Down-Stream process steps :
A large panel of Quality Controls on your batch for in-vitro and in-vivo uses:
Over the years, SYnAbs has developed a strong expertise in development of custom immunoassay and brings its expertise on the table for the optimization of your developed tests.