Anti-mouse antibodies

A secondary monoclonal antibody binds with a primary antibody that is directly attached to the target antigen. Secondary monoclonal antibodies are more sensitive and flexible in labeling and detection and can be used for:

  • ELISA,
  • IH
  • IC,
  • DOT-ELISPOT,
  • cryosection.

SYnAbs developed unique rat monoclonal antibodies targeting the entire repertoire of mouse species, so covering all mouse isotypes. Our anti-mouse secondary antibodies are affinity-purified monoclonal antibodies with well-characterized specificity for mouse immunoglobulin classes.  

They are available in rat species and in the following formats:

  • Unlabeled antibodies
  • Enzyme conjugates (alkaline phosphatase (AP) or horseradish peroxidase (HRP))
  • Fluorescent conjugates (Alexa Fluor, DyLight, Fluorescein (FITC), etc.)
  • Biotin

IgM kappa rat anti-mouse heavy chain

Mu heavy chain - LO-MM-3

Description: IgM kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross-reactivity: Does not bind to rabbit, swine and human IgG. 

Host/Isotype : rat/IgM kappa

 

Download
LO-MM-3 Data Sheet
IgM kappa rat anti-mouse heavy chain - LO-MM-3 SYnAbs data sheet
Data Sheet LO-MM-3 SYnAbs.pdf
Adobe Acrobat Document 211.7 KB

Citations

  • Airway inflammation and IgE production induced by dust mite allergen-specific memory/effector Th2 cell line can be effectively attenuated by IL-35 (In The Journal of Immunology on 1 July 2011 by Huang, C. H., Loo, E. X., et al.)
  • Increased B cell proliferation and reduced Ig production in DREAM transgenic mice (In The Journal of Immunology on 15 December 2010 by Savignac, M., Mellstrom, B., et al.)
  • Bazin H. Production of rat monoclonal antibodies with the LOU rat non secreting IR983F myeloma cell line. Prot. Biol. Fluids, 1982, Peeters E. ed., 29th colloquium 1981 Pergamon Press Oxford and N.Y. : 615-618
  • Cormont F., Manouvriez P., De Clercq L., Bazin H. The use of rat monoclonal antibodies to characterize, quantify and purify polyclonal or monoclonal mouse IgM. Meth. in Enzymol. 1986,121:622-631

IgG1 kappa rat anti-mouse heavy chain

Mu heavy chain - LO-MM-8

 

Description: IgG1 kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Host/Isotype : rat/IgG1 kappa

 

Download
LO-MM-8 Data Sheet
IgG1 kappa rat anti-mouse heavy chain LO-MM-8 SYnAbs data sheet
Data Sheet LO-MM-8 SYnAbs.pdf
Adobe Acrobat Document 207.7 KB

IgG2a kappa rat anti-mouse heavy chain

Mu heavy chain - LO-MM-9

Description: IgG2a kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross-reactivity: Does not bind to human IgM,  IgG, IgA, IgD, IgE isotypes. Does not bind to chicken, rabbit, goat, sheep, bovine, horse, dog, swine, and baboon IgG.

Host/Isotype : rat/IgG2a kappa

 

Download
LO-MM-9 Data Sheet
IgG2a kappa rat anti-mouse heavy chain LO-MM-9 SYnAbs data sheet
Data Sheet LO-MM-9 SYnAbs.pdf
Adobe Acrobat Document 330.1 KB

IgM kappa rat anti-mouse heavy chain

Alpha heavy chain - LO-MA-7

 Description: IgM kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross-reactivity: Does not bind to  human IgG and IgM. Does not bind to chicken, rabbit, goat, sheep, bovine, horse, dog, swine, and baboon IgG.

Host/Isotype : rat/IgM kappa

 

Download
LO-MA-7 Data Sheet
IgM kappa rat anti-mouse heavy chain LO-MA-7 SYnAbs data sheet
Data Sheet LO-MA-7 SYnAbs.pdf
Adobe Acrobat Document 191.3 KB

Citations

 

  • Bazin H. Production of rat monoclonal antibodies with the LOU rat non secreting IR983F myeloma cell line. Prot. Biol. Fluids, 1982, Peeters E. ed., 29th colloquium 1981 Pergamon Press Oxford and N.Y. : 615-618

Alpha heavy chain - LO-MA-10

Description: IgM kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross-reactivity: Does not bind to human IgG and IgM. Does not bind to chicken, rabbit, goat, sheep, bovine, horse, dog, swine, baboon IgG (ELISA test).

Host/Isotype : rat/IgM kappa

 

Download
LO-MA-10 Data Sheet
IgM kappa rat anti-mouse heavy chain LO-MA-10 SYnAbs data sheet
Data Sheet LO-MA-10 SYnAbs.pdf
Adobe Acrobat Document 191.6 KB

IgG2a kappa rat anti-mouse heavy chain

Delta heavy chain - LO-MD-6

 Description: IgG2a kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross reactivity: Does not bind to human IgG and IgM. Does not bind to chicken, rabbit, goat, sheep, bovine, horse, dog, swine, baboon IgG (ELISA test).

Host/Isotype : rat/IgG2a kappa

 

Download
LO-MD-6 Data Sheet
IgG2a kappa rat anti-mouse heavy chain LO-MD-6 SYnAbs data sheet
Data Sheet LO-MD-6 SYnAbs.pdf
Adobe Acrobat Document 224.7 KB

IgG1 kappa rat anti-mouse heavy chain

Delta heavy chain - LO-MD-8

 

Description: IgG1 kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Host/Isotype : rat/IgG1 kappa

 

Download
LO-MD-8 Data Sheet
IgG1 kappa rat anti-mouse heavy chain LO-MD-8 SYnAbs data sheet
Data Sheet LO-MD-8 SYnAbs.pdf
Adobe Acrobat Document 191.3 KB

IgG2a kappa rat anti-mouse heavy chain

Epsilon heavy chain - LO-ME-2

 Description: IgG2a kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross-reactivity: Does not bind to human IgG and IgM. Does not bind to chicken, rabbit, goat, sheep, bovine, horse, dog, swine, baboon IgG (ELISA test).

Host/Isotype : rat/IgG2a kappa

 

Download
LO-ME-2 Data Sheet
Data Sheet LO-ME-2 SYnAbs.pdf
Adobe Acrobat Document 215.4 KB

Epsilon heavy chain - LO-ME-3

 Description: IgG2a kappa rat anti-mouse heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse heavy chain

Cross-reactivity: Does not bind to  human IgG and IgM. Does not bind to chicken, rabbit, goat, sheep, bovine, horse, dog, wine, baboon IgG (ELISA test).

Host/Isotype : rat/IgG2a kappa

 

Download
LO-ME-3 Data Sheet
IgG2a kappa rat anti-mouse heavy chain LO-ME-3 SYnAbs Data Sheet
Data Sheet LO-ME-3 SYnAbs.pdf
Adobe Acrobat Document 188.4 KB

Citations:

 


IgG2a kappa rat anti-mouse kappa light chain

Kappa light chain - LO-MK-1

 

Description: IgG2a kappa rat anti-mouse kappa light chain

Class: monoclonal

Type: secondary 

Antigen: mouse kappa light chain

Host/Isotype : rat/IgG2a kappa

 

Citations:


IgG1 kappa rat anti-mouse kappa light chain

Kappa light chain - LO-MK-2

 

Description: IgG1 kappa rat anti-mouse kappa light chain

Class: monoclonal

Type: secondary 

Antigen: mouse kappa light chain

Host/Isotype : rat/IgG1 kappa

 

Citations:

Download
LO-MK-2 SYnAbs Data Sheet
IgG1 kappa rat anti-mouse kappa light chain LO-MK-2 SYnAbs data sheet
Data Sheet LO-MK-2.pdf
Adobe Acrobat Document 107.2 KB

IgG1 kappa rat anti-mouse IgG1 heavy chain

IgG1 heavy chain - LO-MG1-2


IgG1 heavy chain - LO-MG1-13

Download
LO-MG1-13 SYnAbs Data Sheet
IgG1 kappa rat anti-mouse IgG1 heavy chain LO-MG1-13 SYnAbs data sheet
Data Sheet LO-MG1-13.pdf
Adobe Acrobat Document 113.9 KB

IgG1 heavy chain - LO-MG1-15

 

Description: IgG1 kappa rat anti-mouse IgG1 heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse IgG1 heavy chain

Host/Isotype : rat/IgG1 kappa

 


IgG1 kappa rat anti-mouse IgG1, IgG2a, IgG2b, IgG3 heavy chain

IgG1, IgG2a, IgG2b, IgG3 heavy chain - LO-MGCOC-2


IgG2a kappa rat anti-mouse IgG2a heavy chain

IgG2a heavy chain - LO-MG2a-2

 

Description: IgG2a kappa rat anti-mouse IgG2a heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse IgG1 heavy chain

Host/Isotype : rat/IgG2a kappa

 

Citations:


IgG2a heavy chain - LO-MG2a-3

 

Description: IgG2a kappa rat anti-mouse IgG2a heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse IgG1 heavy chain

Host/Isotype : rat/IgG2a kappa

 

Citations:


IgG1 kappa rat anti-mouse IgG2a heavy chain

IgG2a heavy chain - LO-MG2a-7

 

Description: IgG1 kappa rat anti-mouse IgG2a heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse IgG1 heavy chain

Host/Isotype : rat/IgG1 kappa

 

Download
LO-MG2a-7 SYnAbs Data Sheet
IgG1 kappa rat anti-mouse IgG2a heavy chain LO-MG2a-7 SYnAbs data sheet
Data Sheet LO-MG2a-7.pdf
Adobe Acrobat Document 102.4 KB

IgG2a heavy chain - LO-MG2a-9


IgG1 lambda rat anti-mouse IgG2b heavy chain

IgG2b heavy chain - LO-MG2b-1

 

Description: IgG1 lambda rat anti-mouse IgG2b heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse IgG1 heavy chain

Host/Isotype : rat/IgG1 kappa

 

Download
LO-MG2b-1 SYnAbs Data Sheet
IgG1 lambda rat anti-mouse IgG2b heavy chain LO-MG2b-1 SYnAbs data sheet
Data Sheet LO-MG2b-1.pdf
Adobe Acrobat Document 103.4 KB

IgG1 kappa rat anti-mouse IgG2b heavy chain

IgG2b heavy chain - LO-MG2b-2


IgM kappa rat anti-mouse IgG3 heavy chain

IgG2b heavy chain - LO-MG3-7


IgG1 kappa rat anti-mouse IgG3 heavy chain

IgG2b heavy chain - LO-MG3-13

 

Description: IgG1 kappa rat anti-mouse IgG3 heavy chain

Class: monoclonal

Type: secondary 

Antigen: mouse IgG3 heavy chain

Host/Isotype : rat/IgG1 kappa

 

Citations:

Download
LO-MG3-13 SYnAbs Data Sheet
IgG1 kappa rat anti-mouse IgG3 heavy chain LO-MG3-13 SYnAbs data sheet
Data Sheet LO-MG3-13.pdf
Adobe Acrobat Document 99.7 KB