Testosterone is converted to DHT by 5-alpha reductase. DHT is the active metabolite of testosterone in the urogenital sinus. Most of the circulating DHT concentrations represent the androgen converter (testosterone, androstenedione, DHA and SDHA).

The determination of DHT is of interest in the exploration of hirsutism, especially idiopathic hirsutism in which the concentrations can be increased. Values are very low in 5-alpha reductase deficiency, which are manifested in boys by male pseudo-hermaphroditism at birth.

SYnAbs has first developed a guinea pig monoclonal antibody targeting dihydrotestosterone.

Uniqueness features:

• Higher affinity compared to other species
• Only mAb of guinea pig species on the market

Description: guinea pig anti-dihydrotestosterone

Class: monoclonal

Type: primary 

Cross-reactivity: doesn't bind free testosterone